Metoclopramide Hydrochloride | B3112

Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity with IC₅₀ values of 308 nM and 483 nM, in rat brain cortical membranes and synaptic membranes respectively. It is used as a stimulant of upper gastrointestinal motility and as an antiemetic agent.

Metoclopramide is a 5-hydroxytryptamine (serotonin) 5-HT3 receptor antagonist and dopamine D2 receptor antagonist. Metoclopramide inhibits 5-HT3 receptor and Dopamine D2 receptor binding affinity with IC₅₀ values of 308 nM and 483 nM, in rat brain cortical membranes and synaptic membranes respectively. It is used as a stimulant of upper gastrointestinal motility and as an antiemetic agent.

B3112 | Metoclopramide Hydrochloride DataSheet

Alternate Name/Synonyms: 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride; 4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide hydrochloride; Maxolon

Appearance: White to off-white crystalline powder

Formulation:

CAS Number: 7232-21-5

Structure Available?: TRUE

Peptide sequence:

Salt Form: TRUE

Molecular Formula: C₁₄H₂₃Cl₂N₃O₂

Molecular Weight: 336.26

Cell-Permeable?: True

Purity: ≥ 98%

Solubilities:

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A 5-HT3 and dopamine D2 receptor antagonist

MDL Number: MFCD00058011

PubChem CID: 23659

SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.Cl

InChi: InChI=1S/C14H22ClN3O2.ClH/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3;/h8-9H,4-7,16H2,1-3H3,(H,17,19);1H

InChi Key: RVFUNJWWXKCWNS-UHFFFAOYSA-N