Description
METTL7A Polyclonal Antibody | E-AB-52354 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: AAM B, AAMB, DKFZP586A0522, MET7A, Methyltransferase like 7A, Methyltransferase-like protein 7A, METTL 7A, METTL7A, METTL7A methlytransferase like 7A, Protein AAM-B, Protein AAMB
Application: IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1, 100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human METTL7A
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A