MICU1 Polyclonal Antibody | E-AB-52519

MICU1 Polyclonal Antibody | E-AB-52519 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Allergen Hom s 4, ara CALC, atopy related autoantigen, atopy related autoantigen CALC, Atopy-related autoantigen CALC, CALC, calcium binding atopy related autoantigen 1, Calcium uptake protein 1, calcium uptake protein 1, mitochondrial, Calcium-binding atopy-related autoantigen 1, CBARA1, EFHA3, FLJ12684, MICU1, MICU1, mitochondrial, mitochondrial calcium uptake 1, MPXPS

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Immunology, Signal Transduction

Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human MICU1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A