LBD
MINA Antibody (N-term) [APR30957G]
- SKU:
- LBD-APR30957G
- Availability:
- Usually ships in 5 working days
Description
MINA Antibody (N-term) [APR30957G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This MINA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MINA.
Cellular Localisation: Nucleus. Nucleus, nucleolus
Molecular Weight: 52800
Clone: Polyclonal
Gene Name: RIOX2 (HGNC:19441)
Gene ID: 84864
Function: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Summary: Tissue Location: Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, FC
Dilution: WB--1:1000 FC--1:10~50
Synonyms: Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA, 11411-, 60S ribosomal protein L27a histidine hydroxylase, Histone lysine demethylase MINA, MYC-induced nuclear antigen, Mineral dust-induced gene protein, Nucleolar protein 52, Ribosomal oxygenase MINA, ROX, MINA (HGNC:19441)