MINPP1 Antibody (C-term) [APR17382G]

MINPP1 Antibody (C-term) [APR17382G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-398 amino acids from the C-terminal region of human MINPP1.

Cellular Localisation: Endoplasmic reticulum lumen {ECO:0000250|UniProtKB:O35217}

Molecular Weight: 55051

Clone: Polyclonal

Gene Name: MINPP1

Gene ID: 9562

Function: Acts as a phosphoinositide 5- and phosphoinositide 6- phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) . Also acts as a 2, 3- bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2, 3-bisphosphoglycerate (2, 3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification) . May play a role in the transition of chondrocytes from proliferation to hypertrophy (By similarity) .

Summary: Tissue Location: Widely expressed with highest levels in kidney, liver and placenta.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Multiple inositol polyphosphate phosphatase 1, 3-bisphosphoglycerate 3-phosphatase, 3-BPG phosphatase, Inositol (1, 5) -tetrakisphosphate 3-phosphatase, Ins (1, 5) P (4) 3-phosphatase, MINPP1, MIPP