MIP-1alpha, human recombinant | 4244

Human microphage inflammatory protein-1 (MIP-1 is a 7.8 kDa protein containing 70 amino acid residues. It plays an important role in the inflammatory response of blood monocytes and tissue microphages.

4244 | MIP-1alpha human recombinant DataSheet

Biomolecule/Target: MIP-1 alpha

Synonyms: Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-, MIP-1-, Tonsillar lymphocyte LD78 protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-, PAT 464,1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78, TY-5, SIS-, Heparin-binding chemotaxis protein, L2G25B,

Alternates names: Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF, MGC70609.

Taglines: Recruits and activates polymorphonuclear leukocytes

NCBI Gene ID #: 7422

NCBI Gene Symbol: VEGFA

Gene Source: Human

Accession #: P15692

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: > 95%

Assay: SDS-PAGE

Purity: 98%

Assay #2: HPLC

Endotoxin Level:

Activity (Specifications/test method): The activity was determined by the dose-dependent stimulation of the proliferation of EA.hy926 human endothelial cells with EC50 600 ng/ml.

Biological activity: EC50 is 600 ng/ml. The activity was determined by the dose-dependent stimulation of the proliferation of EA.hy926 human endothelial cells.

Results: 600 ng/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 45 kDa, homodimer, glycosylated

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Sterile filtered and then lyophilized with no additives

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute at 0.2-0.3 mg/mL in distilled water is recommended.

Amino acid sequence: N/A