LBD
MIXL1 Antibody (C-term) [APR04752G]
- SKU:
- LBD-APR04752G
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- Usually ships in 5 working days
Description
MIXL1 Antibody (C-term) [APR04752G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This MIXL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-218 amino acids from the C-terminal region of human MIXL1.
Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:12070013, ECO:0000269|PubMed:17303500}
Molecular Weight: 24659
Clone: Polyclonal
Gene Name: MIXL1
Gene ID: 83881
Function: Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity) .
Summary: Tissue Location: Restricted to progenitors and secondary lymph tissues. In normal hematopoiesis, it is restricted to immature B- and T-lymphoid cells. Present in differentiating embryonic stem cells (at protein level) .
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:500-1:1000
Synonyms: Homeobox protein MIXL1, Homeodomain protein MIX, hMix, MIX1 homeobox-like protein 1, Mix1 homeobox-like protein, MIXL1, MIXL