MK-7655 | B2289

MK-7655 is a potent and selective β-lactamase inhibitor. It restores imipenem-susceptibility in imipenem-resistant K. pneumoniae and P. aeruginosa when used at concentrations of 12.5 and 4.7 μM, respectively.

MK-7655 is a potent and selective β-lactamase inhibitor. It restores imipenem-susceptibility in imipenem-resistant K. pneumoniae and P. aeruginosa when used at concentrations of 12.5 and 4.7 μM, respectively.

B2289 | MK-7655 DataSheet

Alternate Name/Synonyms: [(2S,5R)-7-oxo-2-(piperidin-4-ylcarbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate; Relebactam

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1174018-99-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₂H₂₀N₄O₆S

Molecular Weight: 348.37

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and selective β-lactamase inhibitor

MDL Number: N/A

PubChem CID: 44129647

SMILES: C1CC(N2CC1N(C2=O)OS(=O)(=O)O)C(=O)NC3CCNCC3

InChi: InChI=1S/C12H20N4O6S/c17-11(14-8-3-5-13-6-4-8)10-2-1-9-7-15(10)12(18)16(9)22-23(19,20)21/h8-10,13H,1-7H2,(H,14,17)(H,19,20,21)/t9-,10+/m1/s1

InChi Key: SMOBCLHAZXOKDQ-ZJUUUORDSA-N