MK-8931 | B1315

MK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.

MK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.

B1315 | MK-8931 DataSheet

Alternate Name/Synonyms: (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide; MK-8931

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1286770-55-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₇F₂N₅O₃S

Molecular Weight: 409.41

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent BACE1 inhibitor

MDL Number: N/A

PubChem CID: 51352361

SMILES: CC1(CS(=O)(=O)N(C(=N1)N)C)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)F)F

InChi: InChI=1S/C17H17F2N5O3S/c1-17(9-28(26,27)24(2)16(20)23-17)12-7-11(4-5-13(12)19)22-15(25)14-6-3-10(18)8-21-14/h3-8H,9H2,1-2H3,(H2,20,23)(H,22,25)/t17-/m0/s1

InChi Key: YHYKUSGACIYRML-KRWDZBQOSA-N