MK-8998 | B3212

MK-8998 is a potent and selective antagonist of T-type calcium channel. Could be potentially useful for the treatment of schizophrenia.

MK-8998 is a potent and selective antagonist of T-type calcium channel. Could be potentially useful for the treatment of schizophrenia.

B3212 | MK-8998 DataSheet

Alternate Name/Synonyms: MK8998,(R)-2-(4-isopropylphenyl)-N-(1-(5-(2,2,2-trifluoroethoxy)pyridin-2-yl)ethyl)acetamide

Appearance: Crystalline solid

Formulation:

CAS Number: 953778-58-0

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₃F₃N₂O₂

Molecular Weight: 380.4

Cell-Permeable?: TRUE

Purity: ≥98% by HPLC

Solubilities: >50 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A T type calcium channel antagonist

MDL Number:

PubChem CID: 24765479

SMILES: CC(C)C1=CC=C(C=C1)CC(=O)NC(C)C2=NC=C(C=C2)OCC(F)(F)F

InChi: InChI=1S/C20H23F3N2O2/c1-13(2)16-6-4-15(5-7-16)10-19(26)25-14(3)18-9-8-17(11-24-18)27-12-20(21,22)23/h4-9,11,13-14H,10,12H2,1-3H3,(H,25,26)/t14-/m1/s1

InChi Key: IQIKXZMPPBEWAD-CQSZACIVSA-N