MKS1 Antibody (N-Term) [APR33617G]

MKS1 Antibody (N-Term) [APR33617G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MKS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 90-124 amino acids from the human region of human MKS1.

Cellular Localisation: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme.

Molecular Weight: 64528

Clone: Polyclonal

Gene Name: MKS1

Gene ID: 54903

Function: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC, IF

Dilution: IF--1:25 FC--1:25 WB--1:2000

Synonyms: Meckel syndrome type 1 protein, MKS1