Description
ML-7 hydrochloride is a selective MLCK (myosin light chain kinase) inhibitor (Ki = 0.3 μM). Displays reversible, ATP-competitive inhibition of Ca²⁺-calmodulin-dependent and -independent smooth muscle MLCKs.
ML-7 hydrochloride is a selective MLCK (myosin light chain kinase) inhibitor (Ki = 0.3 μM). Displays reversible, ATP-competitive inhibition of Ca²⁺-calmodulin-dependent and -independent smooth muscle MLCKs.
B2000 | ML-7 hydrochloride DataSheet
Alternate Name/Synonyms: Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepi-ne hydrochloride
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 110448-33-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₇IN₂O₂S.HCl
Molecular Weight: 452.74
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A selective MLCK (myosin light chain kinase) inhibitor
MDL Number: MFCD00065524
PubChem CID: 9803932
SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl
InChi: InChI=1S/C15H17IN2O2S.ClH/c16-14-6-1-5-13-12(14)4-2-7-15(13)21(19,20)18-10-3-8-17-9-11-18;/h1-2,4-7,17H,3,8-11H2;1H
InChi Key: KDDALCDYHZIZMH-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |