Ml241 | 2697

ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100 nM). It blocks p97-dependent proteasome substrate with an IC₅₀ of ~ 3500 nM.

ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100 nM). It blocks p97-dependent proteasome substrate with an IC₅₀ of ~ 3500 nM.

2697 | Ml241 DataSheet

Alternate Name/Synonyms: N-Benzyl-2-(2,3-dihydro-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine;CID49830260

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1346528-06-0

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₄N₄O

Molecular Weight: 372.46

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, selective, and reversible AAA ATPase p97 inhibitor

MDL Number: N/A

PubChem CID: 49830260

SMILES: C1CCC2=C(C1)C(=NC(=N2)N3CCOC4=CC=CC=C43)NCC5=CC=CC=C5

InChi: InChI=1S/C23H24N4O/c1-2-8-17(9-3-1)16-24-22-18-10-4-5-11-19(18)25-23(26-22)27-14-15-28-21-13-7-6-12-20(21)27/h1-3,6-9,12-13H,4-5,10-11,14-16H2,(H,24,25,26)

InChi Key: RMZPVQQGYVSLAP-UHFFFAOYSA-N