MLF1/MLF2 Polyclonal Antibody | BS65449

MLF1/MLF2 Polyclonal Antibody | BS65449 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Pig,Cow,Sheep,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: MLF1/MLF2 Polyclonal Antibody detects endogenous levels of MLF1/MLF2 protein.

Molecular Weight: 31kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Hls7; MLF1; MLF2; MLF3; MLF1_HUMAN; Myelodysplasia myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1; Myeloid leukemia factor 1; myeloid leukemia factor 1 variant 1; myeloid leukemia factor 1 variant 2; myeloid leukemia factor 1 variant 3.

Immunogen: KLH conjugated synthetic peptide derived from human MLF1/2/3:165-268/268

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: