MLH1 Antibody| F41625-0.08ML/F41625-0.4ML/R32088/V7953-20UG

MLH1 Antibody| F41625-0.08ML/F41625-0.4ML/R32088/V7953-20UG | Gentaur UK, US & Europe Distribution

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, FACS, ELISA

Application Details: Western blot: 1:1000, Flow Cytometry: 1:10-1:50

Application Note: Titration of the MLH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This MLH1 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 452-480 from the human protein was used as the immunogen for this MLH1 antibody.

Storage: Aliquot the MLH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A