MLH1 monoclonal Antibody | MB63994

MLH1 monoclonal Antibody | MB63994 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:2000

Background: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: mutL homolog 1

Molecular Weight: 84.4 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: COCA2; FCC2; hMLH1; HNPCC; HNPCC2

Immunogen: Human recombinant protein fragment corresponding to amino acids 299-527 of human MLH1 (NP_000240) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A