MLN2480 | B1706

MLN 2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in clinical trials.

MLN 2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in clinical trials.

B1706 | MLN2480 DataSheet

Alternate Name/Synonyms: MLN2480; ML-N2480; ML N2480; BIIB-024; BIIB024; BIIB 024; TAK-58; TAK580; TAK 580; AMG 2112819; AMG-2112819; AMG2112819; (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide; 2-[(1R)-1-[(6-amino-5-chloropyrimidine-4-carbonyl)amino]ethyl]-N-[5-chloro-4-(trifluoromethyl)pyridin-2-yl]-1,3-thiazole-5-carboxamide

Appearance: Solid

Formulation: N/A

CAS Number: 1096708-71-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₁₂Cl₂F₃N₇O₂S

Molecular Weight: 506.29

Cell-Permeable?: Yes

Purity: >98%

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A selective pan-Raf kinase inhibitor

MDL Number: MFCD22571730

PubChem CID: 25161177

SMILES: CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

InChi: InChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1

InChi Key: VWMJHAFYPMOMGF-ZCFIWIBFSA-N