Description
MLPH Polyclonal Antibody | E-AB-61276 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: MLPH, SLAC2-A
Application: WB, IF
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Neuroscience, Signal Transduction
Background: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant fusion protein of human MLPH (NP_077006.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000 IF 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 50 kDa/52 kDa/60 kDa/62 kDa/65 kDa
Molecular Weight(Observed): 75 kDa