LBD
MME Antibody (Center) [APR04662G]
- SKU:
- LBD-APR04662G
- Availability:
- Usually ships in 5 working days
Description
MME Antibody (Center) [APR04662G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M, Rat
Specificity: This MME antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 492-525 amino acids from the Central region of human MME.
Cellular Localisation: Cell membrane; Single-pass type II membrane protein
Molecular Weight: 85514
Clone: Polyclonal
Gene Name: MME
Gene ID: 4311
Function: Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535) . Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991) . Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675) . Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP (1- 32) ) (PubMed:2531377, PubMed:2972276, PubMed:16254193) . Displays UV- inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573) .
Summary: N/A
Form: N/A
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Neprilysin, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, Enkephalinase, Neutral endopeptidase 2411, NEP, Neutral endopeptidase, Skin fibroblast elastase, SFE, CD10, MME, EPN