Description
The mammalian Matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a single peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contains the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.
5562R | MMP-2 Antibody DataSheet
Antibody Target: MMP-2
Target Alternative Name: MMP2, MMP-2, MMP 2, Matrix metalloproteinase-2, Matrix metalloproteinase 2, Gelatinase A, TBE-1
Tag Line:
Category: MMP
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: E. coli-expressed human MMP-2 (Cat.# 7782-10)
Accession #:
Gene ID:
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-human MMP-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification: Affinity purified
Application: Western blot
Positive Control: E. coli-expressed human MMP-2 (Cat.# 7782-10)
Application And Usages: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Cross-reactivity to MMP-2 of other species has not been determined.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |