MMP3 Antibody | 22-091

MMP3 Antibody | 22-091 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: A synthetic peptide of human MMP3

Research Area: Cancer, Cell Cycle, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:1000
IHC: 1:20 - 1:50
IF: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: HepG2

Positive Control 2: Raji

Positive Control 3: Ramos

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 56kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, pH7.3.

Concentration: N/A

Storage Condition: Store at 4˚C (regular) or -20˚C (long term) . Avoid freeze / thaw cycles.

Alternate Name: CHDS6, matrix metallopeptidase 3 (stromelysin 1, progelatinase) , matrix metalloproteinase 3 (stromelysin 1, matrix metalloproteinase-3, MGC126102, MGC126103, MGC126104, MMP3, MMP-3, OTTHUMP00000045949, proteoglycan, SL-1, STMY, STMY1, STR1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.