MMP7 Polyclonal Antibody | E-AB-10062

MMP7 Polyclonal Antibody | E-AB-10062 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Matrilysin, Matrin, Matrix Metalloproteinase 7, Matrix metalloproteinase-7, MMP 7, MMP-7, MMP7, MMP7, MPSL1, PUMP 1, Pump 1 protease, Pump-1 protease, PUMP1, Uterine matrilysin, Uterine metalloproteinase

Application: WB, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human MMP7

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 30 kDa

Molecular Weight(Observed): N/A