Description
MMP8 Polyclonal Antibody | E-AB-15777 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: CLG 1, CLG1, Collagenase 1, Collagenase 1 neutrophil, HNC, Matrix metallopeptidase 8 (neutrophil collagenase), Matrix metalloprotease 8, Matrix metalloproteinase-8, MMP 8, MMP-8, Mmp8, MMP8, Neutrophil collagenase, PMNL CL, PMNL collagenase, PMNL-CL, PMNLCL
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology, Cardiovascular, Signal Transduction
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human MMP8
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 53 kDa
Molecular Weight(Observed): N/A