MMP9 Antibody (C-term) [APR32255G]

MMP9 Antibody (C-term) [APR32255G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This MMP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644-673 amino acids from the C-terminal region of human MMP9.

Cellular Localisation: Secreted, extracellular space, extracellular matrix

Molecular Weight: 78458

Clone: Polyclonal

Gene Name: MMP9

Gene ID: 4318

Function: Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (PubMed:2551898, PubMed:1480034, PubMed:12879005) . Could play a role in bone osteoclastic resorption (By similarity) . Cleaves KiSS1 at a Gly-|-Leu bond (PubMed:12879005) . Cleaves NINJ1 to generate the Secreted ninjurin-1 form (PubMed:32883094) . Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N- terminal one quarter fragments (PubMed:1480034) . Degrades fibronectin but not laminin or Pz-peptide.

Summary: Tissue Location: Detected in neutrophils (at protein level) (PubMed:7683678) . Produced by normal alveolar macrophages and granulocytes.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:2000 IHC-P--1:100~500

Synonyms: Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB, 67 kDa matrix metalloproteinase-9, 82 kDa matrix metalloproteinase-9, MMP9, CLG4B