MNDA (CT) Antibody | 9645

MNDA (CT) Antibody | 9645 | Gentaur UK, US & Europe Distribution

Product Type: Primary Antibodies

Category: Primary Antibodies, Polyclonal Antibodies, Signal Transduction Antibodies

Research Area: Signal Transduction

Type: Polyclonal

Host Species: Rabbit

Reactivity Species: Human

Homology: Predicted species reactivity based on immunogen sequence: Gorilla (100%), chimpanzee (100%), Monkey (92%)

Immunology: Anti-MNDA antibody (9645) was raised against a peptide corresponding to 13 amino acids near the carboxyl terminus of human MNDA. The immunogen is located within the last 50 amino acids of MNDA.

Tested Application: E, WB, IHC

Application Note: WB: 1 μg/mL; IHC: 2 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples. All other applications and species not yet tested.

Positive Control 1: Cat. No. 1208 - THP-1 Cell Lysate

Positive Control 2: Cat. No. 17-008 – THP-1 Cell Slide

Predicted Molecular Weight: Predicted: 46kD

Observed: 46 kD

Isoform: Human MNDA has one isoform (407aa, 45.8kD) . Mouse MNDA has 2 isoforms, isoform 1 (425aa, 47kD) and isoform 2 (423aa, 46.8kD) . Rat MNDA has one isoform (438aa, 49.7kD) . 9645 can detect MNDA in human, but not in mouse and rat.

Purification: MNDA Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: MNDA Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage: MNDA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Names: MNDA

Protein Accession: P41218.1

User Note: Optimal dilutions for each application to be determined by the researcher.

Background: MNDA Antibody: MNDA controls the expression of MCL-1 and BCL02 in chronic lymphocytic leukemia cells. MNDA is also a useful marker in the recognition and differential diagnosis of marginal zone lymphomas. MNDA has a role in regulating programmed cell death in myeloid progenitor cells, and its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death.

Loading Controls: N/A

Source: N/A

Purity: N/A

CAS: N/A

Shipping Condition: N/A