Description
MNDA (IN) Antibody | 9647 | Gentaur UK, US & Europe Distribution
Product Type: Primary Antibodies
Category: Primary Antibodies, Polyclonal Antibodies, Signal Transduction Antibodies
Research Area: Signal Transduction
Type: Polyclonal
Host Species: Rabbit
Reactivity Species: Human
Homology: Predicted species reactivity based on immunogen sequence: Gorilla (93%), chimpanzee (100%), Monkey (87%)
Immunology: Anti-MNDA antibody (9647) was raised against a peptide corresponding to 15 amino acids near the center of human MNDA. The immunogen is located within 110-160 amino acids of MNDA.
Tested Application: E, IHC, WB
Application Note: WB: 1 μg/mL; IHC: 1 μg/mL. Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples. All other applications and species not yet tested.
Positive Control 1: Cat. No. 1208 - THP-1 Cell Lysate
Positive Control 2: Cat. No. 17-008 - THP-1 Cell Slide
Predicted Molecular Weight: Predicted: 46kD
Observed: 46 kD
Isoform: Human MNDA has one isoform (407aa, 45.8kD) . Mouse MNDA has 2 isoforms, isoform 1 (425aa, 47kD) and isoform 2 (423aa, 46.8kD) . Rat MNDA has one isoform (438aa, 49.7kD) . 9647 can detect MNDA in human, but not in mouse and rat.
Purification: MNDA Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: MNDA Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage: MNDA antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Names: MNDA
Protein Accession: P41218.1
User Note: Optimal dilutions for each application to be determined by the researcher.
Background: MNDA Antibody: MNDA controls the expression of MCL-1 and BCL02 in chronic lymphocytic leukemia cells. MNDA is also a useful marker in the recognition and differential diagnosis of marginal zone lymphomas. MNDA has a role in regulating programmed cell death in myeloid progenitor cells, and its down-regulation in myelodysplastic syndromes is related to granulocyte-macrophage progenitor cell sensitivity to TRAIL-induced programmed cell death.
Loading Controls: N/A
Source: N/A
Purity: N/A
CAS: N/A
Shipping Condition: N/A