BW
MNDA (V406) polyclonal Antibody | BS3332
- SKU:
- BW-BS3332
- Availability:
- Usually ships in 5 working days
Description
MNDA (V406) polyclonal Antibody | BS3332 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: IHC
Application Range: IHC: 1:50~1:200
Background: Interferon-inducible proteins include IFI-202, IFI-203, IFI-204 and D3, which are encoded by six or more structurally related and IFN-inducible mouse genes mapping at the q21-q23 region of chromosome 1. The proteins encoded by these genes have homologous 200 amino acid segments. IFI-202 is a 52 kDa, primarily nuclear phosphoprotein which inhibits cell growth, in part by modulating transcriptional activity of NFκB, E2F, AP-1 and p53. Two related human proteins, MNDA (myeloid cell nuclear differentiation antigen) and IFI-16, have also been described. Expression of MNDA has been observed specifically in cells of the granulocyte-macrophage lineage. IFI-16 is constitutively expressed in various T and B cell lines and can be induced by IFN-γ in HL60 cells. At least four of the Gene 200 cluster of IFN-inducible proteins, IFI-202, IFI-204, MNDA and IFI-16, are localized in the nucleus.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: MNDA (V406) polyclonal Antibody detects endogenous levels of MNDA protein.
Molecular Weight: ~ 46 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Myeloid cell nuclear differentiation antigen; MNDA
Immunogen: Synthetic peptide, corresponding to amino acids 380-430 of Human MNDA.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: