Monochlorobimane | B2671

Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

Monochlorobimane is a cell-permeant probe for quantifying glutathione levels in cells. It is essentially nonfluorescent until it reacts with a thiol group. It readily reacts with several low molecular weight thiols, including cysteine, glutathione, N-acetylcysteine, mercaptopurine, peptides and plasma thiols. The glutathione conjugate of monochlorobimane has an excitation/emission maxima ~394/490 nm.

B2671 | Monochlorobimane DataSheet

Alternate Name/Synonyms: Chlorobimane,NSC602733,7-(chloromethyl)-1,2,6-trimethylpyrazolo[1,2-a]pyrazole-3,5-dione,NSC-602733

Appearance: Yellow solid

Formulation:

CAS Number: 76421-73-3

Structure Available?: Yes

Peptide sequence:

Salt Form: No

Molecular Formula: C₁₀H₁₁ClN₂O₂

Molecular Weight: 226.66

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A cell-permeable glutathione probe

MDL Number: MFCD00077379

PubChem CID: 114886

SMILES: CC1=C(N2C(=C(C(=O)N2C1=O)C)CCl)C

InChi: InChI=1S/C10H11ClN2O2/c1-5-7(3)12-8(4-11)6(2)10(15)13(12)9(5)14/h4H2,1-3H3

InChi Key: SUIPVTCEECPFIB-UHFFFAOYSA-N