MORF4L1 Antibody | XW-8060

MORF4L1 Antibody | XW-8060 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human, Mouse

Homology: N/A

Immunogen: 1-235

Research Area: Other

Tested Application: WB

Application: Mortality factor 4-like protein 1 antibody can be used for the detection of Mortality factor 4-like protein 1 by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 41.5 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: MORF4L1 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: MRG15, FWP006, HSPC008, HSPC061, PP368, Mortality factor 4-like protein 1, MORF-related gene 15 protein, Mortality factor 4like protein 1, Transcription factor-like protein MRG15, MSL3-1 protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.