MORG1 Antibody (Center) [APR32715G]

MORG1 Antibody (Center) [APR32715G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This MORG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human MORG1.

Cellular Localisation: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear.

Molecular Weight: 34343

Clone: Polyclonal

Gene Name: WDR83

Gene ID: 84292

Function: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity) . May also be involved in pre-mRNA splicing.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83, MORG1