Mouse Anti-Human ADAM-17 Antibody | 101-M207

Mouse Anti-Human ADAM-17 Antibody | 101-M207 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#8C13)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B

Isotype: IgG1

Application: WB, FC

Detection Range: WB: 1:500-1000, FC: 1:20-100

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human ADAM-17, also called TACE

Description: The gene for the antigen encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 6868