Mouse Anti-Human Cathepsin E Antibody | 101-M248

Mouse Anti-Human Cathepsin E Antibody | 101-M248 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#4F50)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: CTSE; CATE

Isotype: IgG2

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human Cathepsin-E

Description: Cathepsin E is an intracellular aspartic protease of the pepsin family. Unlike Cathepsin D, another member of the same family and a lysosomal protease with relatively ubiquitous distribution, Cathepsin E is not a lysosomal enzyme and has a limited cell and tissue distribution. However, both Cathepsin D and E play an important role in the degradation of proteins, the generation of bioactive proteins, and antigen processing. Both enzymes are efficient in cleaving Swedish mutant of amyloid precursor protein (APP) at the β site but show almost no reactivity with wildtype APP. Human Cathepsin E is synthesized as a precursor protein, consisting of a signal peptide (aa 1-17), a propeptide (aa 18-53), and a mature chain (aa 54-396).

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 1510