Mouse Anti-Human Coagulation Factor XI Antibody | 101-M332

Mouse Anti-Human Coagulation Factor XI Antibody | 101-M332 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#7C38)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: F11; FXI

Isotype: IgG2

Application: WB, N

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: Human recombinant Coagulation factor XI

Description: Coagulation Factor XI is synthesized in the liver and circulates in the plasma as a disulfide bond-linked dimer complexed with High Molecular Weight Kininogen. Factor XI is converted into active XIa either via the contact phase of blood coagulation or through Thrombin-mediated activation on the platelet surface. The resulting XIa converts Coagulation Factor IX into IXa, which subsequently activates Coagulation Factor X (Xa). Xa then can mediate Coagulation Factor II/Thrombin activation. Patients with factor XI deficiency are prone to excessive bleeding after hemostatic challenge.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 2160