Description
Mouse Anti-Human IL-1 alpha Antibody | 101-M464 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#9F46)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: IL1B; IL-1; IL1F2; IL1-BETA
Isotype: IgG2
Application: WB, IHC (F), N
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: recombinant human IL-1 alpha
Description: IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 3553