Mouse Anti-Human IL-1 R1 Antibody | 101-M466

Mouse Anti-Human IL-1 R1 Antibody | 101-M466 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#5R47)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: IL1R1; P80; IL1R; IL1RA; CD121A; D2S1473; Interleukin 1 receptor 1

Isotype: IgG1

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human IL1-R I EC domain

Description: The Interleukin 1 receptor family comprises at least nine members. All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor) signaling domain that is also conserved in the Toll-like receptor family. A subtype of the IL-1 R family, SIGIRR (single Ig domain-containing IL-1 R-related molecule) differs from the other nine members by having only one Ig domain. IL-1 R1 is a type I transmembrane glycoprotein that functions as the ligand binding subunit in the IL-1 receptor complex. It associates with a signaling component, IL-1 R3 (IL-1 receptor accessory protein) to form a functional receptor complex for IL-1 alpha and IL-1 beta.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 3554