Mouse Anti-Human IL-1F6 Antibody | 101-M497

Mouse Anti-Human IL-1F6 Antibody | 101-M497 | Gentaur UK, US & Europe Distribution

Species: Anti-Human

Host / biotech: Mouse

Comment: N/A

Label: N/A

Clone / Antibody feature: (#3C55)

Subcategory: Monoclonal Antibody

Category: Antibody

Synonyms: IL36A; FIL1; FIL1E; IL1F6; IL-1F6; IL1 (EPSILON); FIL1 (EPSILON)

Isotype: IgG2

Application: WB

Detection Range: N/A

Species Reactivity/Cross reactivity: Human

Antigen: recombinant human IL-1F6

Description: The IL-1 family of cytokines is a set of structurally related molecules that are primary mediators of inflammation. This family now consists of 11 cytokines and 9 cell-surface receptors, the best characterized of which are IL-1α, IL-1β, IL-1 receptor antagonist (IL-1ra), and IL-18. Seven novel members were recently identified from DNA databases almost simultaneously by several different groups, and to reduce confusion, a systematic nomenclature was proposed. IL-1F6, IL-1F8, and IL-1F9 have all reported proinflammatory properties. IL-1F5 shares 52% amino acid similarity with IL-1ra and as such antagonizes IL-1F6 and IL-1F9 at the IL-1R3 (RAcP)–IL-1R6 (Rrp2) receptor complex. IL-1F7 acts as an attenuator of IL-18 activity and may act as an inhibitor of innate immune signaling.

Purity Confirmation: N/A

Endotoxin: N/A

Formulation: lyophilized

Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

Molecular Weight: N/A

Lenght (aa): N/A

Protein Sequence: N/A

NCBI Gene ID: 27179