Description
Mouse Anti-Human Kallikrein 8 Antibody | 101-M534 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#6G15)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: KLK8; NP; HNP; NRPN; PRSS19; TADG14
Isotype: IgG2
Application: WB
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: human recombinant Kallikrein-8
Description: The human tissue kallikrein (KLK) gene family contains 15 members that play important roles in cancer. Notably, kallikrein-1, also known as tissue kallikrein, cleaves kininogen to release the vasoactive kinin peptide, bradykinin or lysyl-bradykinin. Kallikrein-3, called prostate specific antigen (PSA), is an established tumor marker that aids in the diagnosis, staging, and follow up of prostate cancer. Kallikrein-4 is specifically expressed in the prostate and over-expressed in prostate cancer. Kallikrein-5 is widely expressed but found at high levels in skin, breast, brain and testis; over-expression is an indicator of poor prognosis in ovarian cancer. Kallikrein-8 is expressed in the brain and is a novel marker of ovarian and cervical cancer.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 11202