Description
Mouse Anti-Human MIP-1 alpha Antibody | 101-M14 | Gentaur UK, US & Europe Distribution
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: CCL3; MIP1A; SCYA3; G0S19-1; LD78ALPHA; MIP-1-alpha
Isotype: IgG1, kappa
Application: ELISA, N
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: Recombinant Human MIP-1 alpha
Description: Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1α and MIP-1β exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes and MIP-1β selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant human MIP-1α is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized from PBS
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 6348