Mouse BDNF Protein | PRP100400

Mouse BDNF Protein | PRP100400 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from mouse BDNF (P21237) (Met1-Arg249) was expressed and its mature form was purified. The mature form of human, mouse, rat, cynomolgus and canine BDNF sequences are identical.

Activity: Measured by its ability to bind biotinylated human TrkB-His in functional ELISA. Measured by its ability to bind Human TrkB-Fch in functional ELISA. Measured by its ability to bind biotinylated mouse TrkB-His in functional ELISA. 2. Measured by its ability to bind Human TrkB-Fch (Cat:10047-H03H) in functional ELISA. 3. Measured by its ability to bind biotinylated mouse TrkB-His (Cat:50132-M08H) in functional ELISA.

protein Lenght: The recombinant mature form of mouse BDNF consists of 119 amino acids and predicts a molecular mass of 13.5 KDa.

Preparation: CHO Stable Cells

Purity: > 95 % as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS

Kit Component: N/A

Features & Benefits : N/A

Molecular Weight: 13.5 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse BDNF protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Mouse BDNF Proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.84% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Alternative Names: Brain-derived neurotrophic factor; BDNF

Search Names: Brain-derived neurotrophic factor; BDNF

Tag: BDNF