(Mouse) Dpf2 Antibody (N-term) [APR33060G]

(Mouse) Dpf2 Antibody (N-term) [APR33060G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This mouse Dpf2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from the N-terminal region of mouse Dpf2.

Cellular Localisation: Nucleus {ECO:0000250|UniProtKB:Q92785}. Cytoplasm {ECO:0000250|UniProtKB:Q92785}

Molecular Weight: 44230

Clone: Polyclonal

Gene Name: Dpf2

Gene ID: 19708

Function: Plays an active role in transcriptional regulation by binding modified histones H3 and H4. Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (By similarity) . Might also have a role in the development and maturation of lymphoid cells (PubMed:7961935) . Involved in the regulation of non-canonical NF- kappa-B pathway (By similarity) .

Summary: Tissue Location: In embryo, highest levels are seen in brain, eyes, thymus and olfactory epithelium in nose, whereas several other tissues, including the musculoskeletal system, show moderate expression. In adult, higher expression in testis, medium in thymus and spleen, lower in certain parts of the brain as the hippocampus. No expression in adult heart, lung, liver, duodenum and kidney

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, IHC-P

Dilution: IHC-P--1:100~500 WB--1:2000

Synonyms: Zinc finger protein ubi-d4, Apoptosis response zinc finger protein, BRG1-associated factor 45D, BAF45D, D4, zinc and double PHD fingers family 2, Protein requiem, Dpf2, Baf45d, Req, Ubid4