Mouse Eef2k Antibody (N-term) [APC00083G]

Mouse Eef2k Antibody (N-term) [APC00083G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Eef2k antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the N-terminal region of mouse Eef2k.

Cellular Localisation: N/A

Molecular Weight: 81739

Clone: Polyclonal

Gene Name: Eef2k

Gene ID: 13631

Function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Summary: Tissue Location: Ubiquitously expressed. Particularly abundant in skeletal muscle and heart

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, Eef2k