Mouse Erbb3 Antibody (P1076) [ApR04816G]

Mouse Erbb3 Antibody (P1076) [ApR04816G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Erbb3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1076-1110 amino acids from the region of Mouse Erbb3.

Cellular Localisation: Membrane; Single-pass type I membrane protein

Molecular Weight: 147613

Clone: Polyclonal

Gene Name: Erbb3

Gene ID: 13867

Function: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5. Involved in the regulation of myeloid cell differentiation.

Summary: Tissue Location: In the muscle, expression localizes to the synaptic sites of muscle fibers

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Receptor tyrosine-protein kinase erbB-3, Glial growth factor receptor, Proto-oncogene-like protein c-ErbB-3, Erbb3