Mouse Frk Antibody (C-term) [APR04717G]

Mouse Frk Antibody (C-term) [APR04717G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M, Rat

Specificity: This Mouse Frk antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 482-516 amino acids from the C-terminal region of human Mouse Frk.

Cellular Localisation: Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery.

Molecular Weight: 58844

Clone: Polyclonal

Gene Name: Frk

Gene ID: 14302

Function: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor (By similarity) .

Summary: Tissue Location: Expressed in intestinal tract, fetal and adult islets of Langerhans, kidney, liver and lung

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:500-1:1000

Synonyms: Tyrosine-protein kinase FRK, Beta-cell Src-homology tyrosine kinase, BSK, FYN-related kinase, Intestine tyrosine kinase, Frk, Bsk, Iyk