(Mouse) Gnl3 Antibody (C-term) [APR11353G]

(Mouse) Gnl3 Antibody (C-term) [APR11353G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Gnl3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 450-483 amino acids from the C-terminal region of mouse Gnl3.

Cellular Localisation: Nucleus. Nucleus, nucleolus. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}

Molecular Weight: 60786

Clone: Polyclonal

Gene Name: Gnl3

Gene ID: 30877

Function: May be required to maintain the proliferative capacity of stem cells (By similarity) . Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation.

Summary: Tissue Location: Expressed in the adult bone marrow population that is enriched in hematopoietic stem cells.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Guanine nucleotide-binding protein-like 3, Nucleolar GTP-binding protein 3, Nucleostemin, Gnl3, Ns