Mouse IL-13 protein, His tag (Animal-Free) | PRP2114

Mouse IL-13 protein, His tag (Animal-Free) | PRP2114 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines (Animal-Free)

Sequence: Amino acid sequence derived from mouse IL-13 protein (P20109, Met1-Phe131) was expressed with a polyhistidine tag at the C-terminus.

Activity: N/A

protein Lenght: The recombinant mouse IL-13 protein consists of 118 amino acids and predicts a molecular mass of 12.7 kD.The apparent molecular mass of the mouse IL-13 is approximately 15-30 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Preparation: HEK 293 Cells

Purity: >95% as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS, pH 7.4.

Kit Component: N/A

Features & Benefits : Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 12.7kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized mouse IL-13 protein in the buffer which we provide not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Mouse IL-13 protein, His tag (Animal-Free) should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.119% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: Interleukin (IL) -13, a cytokine produced by T helper 2 (Th2) cells, is a powerful inhibitor of macrophage functions, including surface expression of CD14 and production of IL-1 and tumor necrosis factor (TNF) -α. Interleukin (IL) -13 synergizes with IL-2 in regulating interferon-gamma synthesis . It may be critical in regulating inflammatory and immune responses .Mouse IL-13 shares 58% sequence identity with human protein and exhibits cross-species activity.IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4.

Alternative Names: ALRHMGC116789; BHR1interleukin-13; IL13; IL-13; IL-13MGC116788; interleukin 13; MGC116786; NC30; P600

Search Names: ALRHMGC116789; BHR1interleukin-13; IL13; IL-13; IL-13MGC116788; interleukin 13; MGC116786; NC30; P600

Tag: IL-13