Mouse Lrmp Antibody (C-term) [APR31877G]

Mouse Lrmp Antibody (C-term) [APR31877G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Lrmp antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 403-431 amino acids from the C-terminal region of mouse Lrmp.

Cellular Localisation: [Processed inositol 1, 4, 5-triphosphate receptor associated 2]: Cytoplasm

Molecular Weight: 59588

Clone: Polyclonal

Gene Name: Irag2

Gene ID: 16970

Function: Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP) -independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion (PubMed:9314557) . Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules (PubMed:29878215) .

Summary: Tissue Location: Spleen and thymus. Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in circumvallate (CV), foliate (FL) and fungiform (FF) taste papillae cells of the tongue epithelium.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Lymphoid-restricted membrane protein, Protein Jaw1, Processed lymphoid-restricted membrane protein, Lrmp, Jaw1