Mouse Mast1 Antibody (C-term) [APR17430G]

Mouse Mast1 Antibody (C-term) [APR17430G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Mast1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1438-1464 amino acids from the C-terminal region of mouse Mast1.

Cellular Localisation: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Note=Also localized in the soma of neurons (PubMed:30449657) . Observed as punctate clusters in the processes of interneurons and along the cell body periphery Colocalizes with syntrophins at the cell membrane

Molecular Weight: 170997

Clone: Polyclonal

Gene Name: Mast1 {ECO:0000312|MGI:MGI:1861901}

Gene ID: 56527

Function: Microtubule-associated protein essential for correct brain development (PubMed:30449657) . Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins.

Summary: Tissue Location: Expressed in the brain (PubMed:30449657) . Expressed in the developing cortical plate, the intermediate zone and corpus callosal fibers that cross the midline (PubMed:30449657) . Detected at low levels in the testis, liver and spleen (PubMed:30449657) . Expressed in proximity to neuronal nuclei throughout the cortex and cerebellum, and in the vascular endothelium. Also detected in ependymal cells, the choroid plexus, and in developing spermatid acrosomes

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Microtubule-associated serine/threonine-protein kinase 1, Syntrophin-associated serine/threonine-protein kinase, Mast1 {ECO:0000312|MGI:MGI:1861901}