(Mouse) Msi1 Antibody (Center) [APR11356G]

(Mouse) Msi1 Antibody (Center) [APR11356G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This mouse Msi1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 81-113 amino acids from the Central region of mouse Msi1.

Cellular Localisation: Cytoplasm. Nucleus

Molecular Weight: 39119

Clone: Polyclonal

Gene Name: Msi1

Gene ID: 17690

Function: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU- 3' and other sequences containing the pattern 5'-[GA]U (1-3) AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

Summary: Tissue Location: Expressed in neural stem and progenitor cells (at protein level) (PubMed:16554442) . Detected in olfactory bulb, brain stem, small intestine, and at low levels in brain cortex, hippocampus and ovary (PubMed:8660864) . Detected in neural progenitor cells, including neural stem cells (PubMed:8660864)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: RNA-binding protein Musashi homolog 1, Musashi-1, Msi1, Msi1h