Mouse Noto Antibody (C-term) [APR32999G]

Mouse Noto Antibody (C-term) [APR32999G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Noto antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 200-234 amino acids from the C-terminal region of Mouse Noto.

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.

Molecular Weight: 26322

Clone: Polyclonal

Gene Name: Noto

Gene ID: 384452

Function: Transcription factor that controls node morphogenesis (PubMed:15231714, PubMed:17884984, PubMed:18061569, PubMed:22357932) . Acts downstream of both FOXA2 and Brachyury (T) during notochord development (PubMed:15231714) . Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function (PubMed:17884984) . Plays a role in regulating axial versus paraxial cell fate (PubMed:18061569) . Activates the transcription of ciliary proteins C11orf97 homolog, FAM183B and SPACA9 in the embryonic ventral node (PubMed:27914912) .

Summary: N/A

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Homeobox protein notochord, Noto, Not