Mouse Pdk3 Antibody (C-term) [APR07135G]

Mouse Pdk3 Antibody (C-term) [APR07135G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: M

Specificity: This Mouse Pdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-414 amino acids from the C-terminal region of mouse Pdk3.

Cellular Localisation: Mitochondrion matrix.

Molecular Weight: 47923

Clone: Polyclonal

Gene Name: Pdk3

Gene ID: 236900

Function: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: [Pyruvate dehydrogenase (acetyl-transferring) ] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, Pdk3